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My research interests are primarily concerned with the design, synthesis and resolution of multidentate ligands containing stereogenic arsenic and/or phosphorus donor atoms and the role of their transition metal based complexes as potential antitumour agents or as catalysts in asymmetric synthesis.
Geoff Salem is the Associate Director of Education of the Research School of Chemistry.
PhD Candidates |
A range of chiral multidentate ligands with As2NP, As4P, As4, As6, P2N2, P4 and very recently P6 and N3P3 donor sets have been synthesised via the coupling of appropriately designed bidentate precursors and often in a highly stereoselective manner.
More about Chiral Multidentate Ligands with Stereogenic As and or P Donor Atoms
A wide range of transition metal complexes have been prepared containing the aforementioned ligands with [Au(P4)]+ cations and dinuclear compounds of the type [(PtClMe)2(μ-P2N2)] being of particular current interest as potential antitumour agents.
More about Chiral Transition Metal Complexes as Potential Anticancer Drugs
More recent achievements include: