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Our research interests include the development of new synthetic methods and the chemical synthesis of biologically active natural products. Challenging target structures stimulate the development of new and efficient strategies for chemical synthesis. The development and exploitation of chemical catalysis is central to many of these endeavours. Our group is also focused on the application of such synthesis to wider problems and collaborates closely with others such as the interaction of small molecules with complex biological systems and work on developing sports drug testing.
Malcolm McLeod graduated from Monash University with a BSc (hons) and received a DPhil from the University of Cambridge.
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Catalysis is a central tenet of modern organic synthesis. It allows for the efficient, atom economic and scalable conversion of starting materials to products, often with high levels of absolute or relative stereocontrol.
This research is conducted in close collaboration with the Australian Racing Forensic Laboratories (ARFL) located in Randwick, NSW, and aims to develop new methods for illicit drug detection in thoroughbred, harness and greyhound racing.
We are developing efficient strategies for the synthesis of natural products with important biological activity. Targets include the microsclerodermin family of antifungal cyclic peptides.
More about Total Synthesis of Biologically Active Natural Products and Analogues