DNA-based biotechnologies are rapidly forming a new landscape in the world of technology and innovation. However accurate identification of a specific DNA-sequence (e.g. as produced through nucleic acid amplification) still requires high-end equipment and complex protocols. Together with colleagues at the CSIRO (Health & Biosecurity) we are harnessing the power of biological recognition for the production of new biosensors that are able to rapidly identify specific ds-DNA sequences. These allow accurate detection/quantitation of a target DNA sequence and are amenable to application with low-cost analytical technologies in primary laboratories and at point-of-care.