Designing cooperative transition metal catalysts

Transition metal catalysts are pervasive throughout synthetic, industrial and biological chemistry. Traditionally, catalytic activation of substrates occurs at the metal centre. Molecular cooperativity, wherein bifunctional substrate activation occurs across multiple sites within a catalyst, offers a powerful route to improve catalytic efficiency and selectivity, and develop new catalytic processes. We are interested in designing catalyst architectures which promote molecular cooperativity, and investigating the role of both metal-ligand cooperativity and metal-metal cooperativity in enabling efficient catalytic processes.