Hardware configuration

LC: Dionex Ultimate 3000 UHPLC (analytical, micro- or nano-flow)

MS: Thermo Orbitrap Fusion Quadrupole / Ion Trap / Orbitrap Tribrid ETD

• Analytical flow or nanospray ESI
• Mass resolution up to 500,000
• Mass error <1 ppm
• Scanning up to 20 spectra / sec
• HCD, CID and Electron Transfer Dissociation (ETD) modes of fragmentation
• MSⁿ analysis
• Integrated syringe pump for LC-independent sample introduction

Key applications

• Proteomics, including analysis of post-translational modifications
• Intact proteins / protein complexes
• Metabolomics / chemometrics
• Highly sensitive target quantification
• Accurate mass characterisation of synthetic molecules

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