RSC School Seminar - Dr Nicole Rijs (UNSW)

Title: Exploring chemical complexity with ion mobility mass spectrometry

schedule Date & time
28 Mar 2024 12:00pm - 28 Mar 2024 1:00pm
person Speaker


Dr Nicole Rijs
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Malin Finell
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RSC School Seminar - Nicole Rijs 28.03.2024

Exploring chemical complexity with ion mobility mass spectrometry


Full synthetic implementation of many types of chemical complexity is hampered by an inability to efficiently characterise complex mixtures. In this talk, I will discuss our explorations of chemical space in complex systems using ion mobility mass spectrometry1 with examples of metallo-supramolecular self-assembly,2 host-guest interactions, metal-mediated chemistry,3 and structurally labile complexes of zwitterionic molecules. The structural information gained from ion mobility is highly useful, although the structural analysis of metal containing species is as yet somewhat nascent. I will discuss some of the pros and cons of ion mobility mass spectrometry and things to be mindful of with both experimental and theoretical “collisional cross sections”, together with mechanistic findings.

1. Front. Chem., 2021, 9:682743.

2. Angew. Chem. Int. Ed., 2024, 63, e202313892.

3. J. Am. Chem. Soc., 2016, 138, 3125–3135


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