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Organic chemistry to drug discovery and back again

Abstract

Drug discovery can provide a vast array of structures to inspire organic chemistry. Whether it necessitates methodology development, applying known chemistry to new molecules or generating novel functionality, the pursuit of pharmaceuticals is hugely beneficial to organic chemistry.

This talk will showcase the generation of an active pharmaceutical ingredient, steps in process development and compound stability and solubility. It will show how a compound developed in an academic lab has progressed to human clinical trials and the lessons synthetic chemists can learn along the way. I will also show new chemical and biological work that is underway in my group at UNSW Canberra.