3D Electron Diffraction / MicroED at ANU (co-supervisor Dr. Felipe Kremer, CAM)
This project establishes a MicroED facility at ANU to study small molecule crystal structures using electron crystallography, enabling analysis of tiny crystals and advancing structural chemistry through specimen prep, data collection, and analysis.
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About
Knowing the 3D atomic structures is crucial for designing novel materials with extraordinary properties, discovering new drugs to treat disease, studying chemical and biological molecules, and understanding fundamental chemical and biological processes. While traditional crystallography methods have been instrumental in deciphering crystal structures, they face limitations when dealing with tiny crystals. With the development of electron crystallography methods, scientists can explore previously inaccessible realms, solve complex structures and answer questions that were once deemed unapproachable. With this project, we will setup a robust 3D ED/MicroED workflow for studying crystals structures of small molecules at ANU, which includes specimen preparation, data collection and data analysis. The aim of the project is to establish one of the first MicroED facilities in Australia, making this exciting method available to Australian scientists. The student will have the opportunity to work with electron microscopes, learn electron crystallography and gain knowledge and research experiences in structural chemistry.