The development of hierarchically-structured engineered living materials
The successful candidate will get to leverage to power of biology to create completely artificial engineering living materials that can adapt their structures to the external environment.
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Engineered Living Materials (ELM) are an exciting new class of matter, where the global aim is to create functional, tough, hierarchically ordered materials, by leveraging the biologically activity of living cells. In nature, examples of these high-performance inorganic-organic composite biomaterials are widespread, ranging from nacre (mother of pearl) to the frustules of diatoms. However, a major challenge is using engineered microorganisms in the lab to generate highly ordered macroscale structures from microscale units. Accordingly, the focus of this project is on the rational design and characterization of hierarchically ordered composite living materials. In doing so, the successful candidate will engineer bacteria and yeast to produce biopolymer fibres and enzymes in 3D printed structures and microfluidic devices, enabling controllable formation of hierarchically ordered tough biomaterials with emergent functions, such as mechanoresponsive remodelling and self-healing.
