Protein NMR spectroscopy

Most proteins and enzymes "live" in solution. Like mechanical machines, their function depends on conformational changes. Using NMR spectroscopy in solution, we develop new methods to determine the movements and conformational changes of proteins, such as the COVID-19 main protease.

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This project is open for Honours, Master, PhD and Summer scholar students.
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Gottfried Otting
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Group Leader

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Most proteins and enzymes "live" in solution. Like mechanical machines, their function depends on conformational changes. Using NMR spectroscopy in solution, we develop new methods to determine the movements and conformational changes of proteins, such as the COVID-19 main protease, which are inaccessible by any other experimental technique.

Protein NMR spectroscopy