We use NMR spectroscopy to assess the structural changes of proteins in response to other molecules in aqueous solution, i.e. under near-physiological condition

label Research theme


We work with drug discovery, developing new methods to analyse the structures of protein-ligand complexes in solution by NMR spectroscopy.

We use cell-free protein synthesis as one of our main tools and have leading expertise in the use of unnatural amino acids for site-specific protein modification (for example with tags that allow rapid determination of the binding site, binding orientation and structure of ligand molecules).


The group develops techniques to attach chemical tags to proteins site-specifically, to enable convenient analysis by NMR and EPR spectroscopy. This includes the use of cell-free protein synthesis with bespoke unnatural amino acids and specific labelling techniques. More at rsc.anu.edu.au/~go/index.html

Student intake

Open for Honours, PhD students


Physical and Biophysical Chemistry



ARC Laureate Fellow


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Postdoctoral Fellow

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Postdoctoral Fellow

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Postdoctoral Fellow



Spotlights on Recent JACS Publications has highlighted a JACS paper recently published by Elwy Abdelkader, Haocheng Qianzhu, Yi Jiun Tan, Luke Adams, Thomas Huber and Gottfried Otting (10.1021/jacs.0c11971).

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