Medicinal Chemistry and Drug Development
About
Medicinal chemistry is focused on the development of drugs, which could be either small molecules or peptides and proteins, for treatment of disease. Modern medicinal chemistry and drug development is highly interdisciplinary and encompasses synthetic organic chemistry, enzymology, biophysical techniques (including protein NMR, protein crystallography and the study of protein-ligand interactions), computational chemistry, protein engineering and pharmacology.
Groups
Our research interests lie at the interface between biology, chemistry and physics where fundamental chemistry underlies biological function.
The Malins group develops synthetic tools for small molecule, peptide and protein synthesis, including for applications in chemical biology and drug discovery.
The McLeod group employs a wide range of techniques to study drug metabolism.
We develop chemical tools to target, manipulate and study peptides and proteins related to infectious diseases.
Our research program involves the design of sequences of cycloaddition reactions, free radical reactions and transition metal-mediated reactions
In Xu group, our mission is to develop new electron crystallography methods for crystal structure characterisation, at the same time, improving the capability, robustness and availability of these methods. By doing so, we aim to equip chemists, biologists, and material scientists with innovative tools for ground breaking research.
The Zhang group uses chemical and synthetic biology to engineer proteins and create novel protein functionality, integrating protein chemistry, biophysics, molecular biology and cell biology.
Facilities
Providing synthetic and separative solutions to the RSC
Projects
Members
Academic staff
Professor
Professor
Westpac Research Fellow
Associate Professor
Associate Professor
ARC Future Fellow
Associate Director (Education)
Professor
Lecturer
Rita Cornforth Fellow
Emeritus and Honorary
Honorary Professor
News
Fighting antibiotic resistance takes guts. Dr Lara Malins discusses her research into antibiotic resistance.