The McLeod group employs a wide range of techniques to study drug metabolism.

About

The McLeod group employs a wide range of techniques to study drug metabolism. These include chemical and enzymatic synthesis of drugs and their metabolites, methods of in vitro metabolism coupled with analysis by GC-MS-MS or LC-MS-MS, and molecular biology to engineer improved enzymes with anti-doping applications.

The group is also active in the area of medicinal chemistry of nicotinic acetylcholine receptors (nAChRs). Here our goal is the development of new drugs to treat neurological disorders and the application of tools like covalent trapping, an extension of the substituted cysteine accessibility method, to better understand where drugs bind on nAChRs.

Publications

Projects

A Trojan horse to combat malaria, Anti-doping chemistry, Enzyme engineering and Exploring the ‘sulfatome’.

Student intake

Open for Honours, PhD students

Theme

Analytical Chemistry and Sensors, Catalysis, Medicinal Chemistry and Drug Development, Organic chemistry

Members

Leader

Associate Professor

Student

No photo provided

PhD Candidate

No photo provided

Honours Student

No photo provided

Honours Student

PhD Candidate

No photo provided

PhD Candidate

No photo provided

Postdoctoral Fellow

No photo provided

Postdoctoral Fellow

No photo provided

PhD Candidate

No photo provided

PhD Candidate

News

Congratulations to Associate Professor Malcolm McLeod - 2020 Churchill Fellowship Award Recipient.

Read the article