Hydrogen is well recognized for its potential as a future energy source – but few people are aware of another
remarkable ability of the simple H2 molecule. The challenge is this: how can we incorporate para-hydrogen into molecules?

Our goal is to develop an anti-malarial Trojan horse that will deliver a chemical payload to the malaria parasite that it cannot avoid, thus limiting the potential for resistance.

This project will explore additional opportunities for the efficient electrochemical modification of peptides, including through the use of novel “electrochemically-active” amino acids.

This project will combine analytical and synthetic chemistry to study the metabolic fate and biological activity arising from designer steroids use, with the goal of developing assays to detect the abuse of these agents in sport.

We are studying compounds in which a single atom of carbon is held between two metal centres LnM=C=MLn. In most cases the M=C=M spine is linear but we have recently isolated the first examples where the carbon is bent and displays nucleophilic character.

This project will capitalise on these achievements and explore biocompatible synthetic routes to various kinds of bicycles and their applications in drug discovery.