Organic chemistry

Organic chemistry

We are increasingly able to manipulate and control the structure and behaviour of individual molecules and even atoms – nanotechnology. This opens up the exciting possibility of controlling the fundamental properties of materials such as colour, strength and electrical conductivity.

About

Organic substances are everywhere: they are the basis of all life forms and central to our heath and wellbeing. Organic chemistry is the study of the structure, properties and syntheses of carbon-containing compounds, and includes both compounds produced by living organisms as well as designed molecules. The range of application of organic compounds is enormous. The very foundations of biochemistry, biotechnology, and medicine are built on organic compounds and their role in life processes. Most modern, high-tech materials are at least partially composed of organic compounds. Organic chemists at all levels are employed by pharmaceutical, biotech, chemical, consumer product, food and petroleum industries. 

Groups

Liquid metal

Our work covers organometallic chemistry with a particular focus include unsaturated ligands involving metal–carbon multiple bonding.

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Humphrey

Our research uses synthesis, spectroscopy, electrochemistry, and computational chemistry to generate new molecular materials with unusual optical properties.

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Malins group

The Malins group develops synthetic tools for small molecule, peptide and protein synthesis, including for applications in chemical biology and drug discovery.

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Drug chemistry

The McLeod group employs a wide range of techniques to study drug metabolism.

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A male scientist wearing glasses, a lab coat, and protective gloves smiles at the camera in a chemical laboratory setting.

We develop chemical tools to target, manipulate and study peptides and proteins related to infectious diseases.

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Organic molecule

The Norcott group research interest centres on using organic synthesis and reactivity to design new, functional molecules with important purposes.

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Organic molecule

Our research program involves the design of sequences of cycloaddition reactions, free radical reactions and transition metal-mediated reactions

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Five young adults smiling and standing together in front of a metal building covered with vines.

Our research focuses on supramolecular chemistry – the chemistry of non-covalent interactions such as hydrogen bonding, halogen bonding and coordination bonds. 

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Facilities

Separation and Reaction Facility

Providing synthetic and separative solutions to the RSC

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Projects

This project will explore designer bicyclobutanes and the strained molecule “propellane” in alkylation, radical addition and cycloaddition chemistry, including for the modification of peptides and bioactive small molecules.

Student intake

Open for Honours, Master, PhD, Summer scholar students

Structurally complex organic natural products are the basis of most of our medicines, and people trained in their
preparation are employed in discovery and process chemistry research units of pharmaceutical companies.

Student intake

Open for Honours, Master, PhD, Summer scholar students

The Malins group is interested in several anti-cancer, antimalarial, and antibiotic peptides. 2023-2024 projects in this space will involve the chemical synthesis, structural modification, and biological evaluation of peptide leads as next-generation therapies.

Student intake

Open for Honours, Master, PhD, Summer scholar students

Molecules that, in structural terms, go beyond the boundaries of what is currently known both improve our
understanding of fundamental science, and have the potential for exciting and important downstream applications.

Student intake

Open for Honours, Master, PhD, Summer scholar students

Facile lithium/halogen exchange with BuLi affords lithiocarbynes which in turn react with a range of electrophiles. Using these strategies we have isolated examples of carbyne ligands based on B, Si, Ge, Sn, Pb, P, As, Sb and Bi, e.g.,the tris(carbyne)silane H–Si(CMLn)3 shown.

Student intake

Open for Honours, Master, PhD, Summer scholar students

This project will explore the synthesis and characterization of new π-delocalizable oligomers and dendrimers at the interface between organic/organometallic chemistry and polymer science.

Student intake

Open for Honours, Master, PhD, Summer scholar students

Members

Emeritus and Honorary

Honorary Lecturer

Honorary Professor

Emeritus Professor

Academic staff

Professor
Westpac Research Fellow

Associate Professor

Associate Professor Christoph Nitsche

Associate Professor
ARC Future Fellow

Associate Director (Education)
Professor

Nick White 2023

Associate Professor
Australian Research Council Future Fellow

News

Congratulations to Dr Nick White who has been awarded an ARC Future Fellowship. This is fantastic news, and a tribute to all of Nick’s hard work and achievements in supramolecular chemistry.

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Fighting antibiotic resistance takes guts. Dr Lara Malins discusses her research into antibiotic resistance.

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